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The GPCRs: Concept structure art by Nicholas Rajan (@nicks_dfg ) made with @procreate
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters, and vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases, and are also the target of approximately 34% of all modern medicinal drugs.
There are two principal signal transduction pathways involving the G protein-coupled receptors:
* the cAMP signal pathway and
* the phosphatidylinositol signal pathway.
When a ligand binds to the GPCR it causes a conformational change in the GPCR, which allows it to act as a guanine nucleotide exchange factor (GEF). The GPCR can then activate an associated G protein by exchanging the GDP bound to the G protein for a GTP. The G protein's α subunit, together with the bound GTP, can then dissociate from the β and γ subunits to further affect intracellular signaling proteins or target functional proteins directly depending on the α subunit type (Gαs, Gαi/o, Gαq/11, Gα12/13)
#biotechnologystudent #scienceporn #learning #science #biology #cellbiology #genetics #gproteincoupledreceptors #medicine #cellsignaling #cellsignal #cellsignalingtechnology #cellscience #receptors #cell #cellsatwork #cellbiology #molecularbiology #molecularbiologyandgenetics #cancerresearch #celldeath #cancerdrugs @sciencechannel @biologyminds @nanobioart @sketchingscience #scienceporn #biotech #biomedical #
Oh my Biology Gangs! Tag all your biology and life science groups.
Follow us @labmonkofficial
#labmonk #biology #biologymajor #biologyjokes #biologynotes #biologyteacher #biologystudent #bioscience #microbiology #biotechnology #molecularbiology #marinebiology #cellbiology #plantbiology #animalbiology #humanbiology #lifescience #cellscience #bacteriology #virology #marinescience #aquatic #fishery #botany #zoology #pharmacy #science #pharmacystudent
世界80カ国以上で愛されてきたスキンケアブランド、オレイが日本に上陸✈️ プレステージライン「オレイ リジェネリスト」をオンライン限定で発売中です✨.
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ラインナップは、洗顔料、化粧水、美容液、美容クリームのシンプルかつパワフルな4製品。化粧水はまろやかなテクスチャーで肌にのせたときの密着感が◎。ふっくらハリ感が出るのもうれしい! スターアイテムの美容液は、瑞々しく肌なじみがよく、甘い香りで気分があがります⤴️
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うるおいが長時間続き、使い続けるほどにスッと冴え渡るような、シャープなハリ肌へ。60年以上の歴史と確かな研究に裏付けられたオレイ、その実力はライン使いでお試しあれ〜❗️.
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◆画像1枚目 右から
オレイ リジェネリスト トナー 6000円(税抜・編集部調べ)
オレイ リジェネリスト クレンザー 3500円(税抜・編集部調べ)
オレイ リジェネリスト クリーム 6870円(税抜・編集部調べ)
オレイ リジェネリスト エッセンス 8000円(税抜・編集部調べ) .
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シリーズ全パッケージに入ったこのお顔が、個人的には萌えポイント❣️レトロかわいいロゴが目印です♀️.
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編集iw
#オレイ #オレイリジェネリスト #洗顔料 #化粧水 #美容液 #クリーム #スキンケア #日本上陸 #海外コスメ #olay #olayregenerist #cellscience #olay28day #maquia #マキア
This image is of a Human Spinal Nerve. Spinal nerves are part of the peripheral nervous system. They run within the spinal column to carry nerve signals to and from all parts of the body. The spinal nerves enable all the movements we do, from turning our heads to wiggling our toes, control the movements of our internal organs, such as the colon and the bladder, as well as allow us to feel touch and location of our limbs.
: Tom Deerinck and Mark Ellisman, National Center for Microscopy and Imaging Research
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#Science #TheScienceExplorer #TechnologyNetworks #ScienceIsCool #ScienceInstagram #ScienceImage #SciencePhotography #InstaScience #ScienceResearch #IOTD #ImageoftheDay #CellScience #Microscopy #ScienceImaging
Thank you for having me as your guest-doctor this month @cureclinic See you next month. Menyenangkan bekerja dgn team Cure Clinic di Griya Cure - Jakarta. Produk yang dipakai dijamin Asli dan berkualitas. Book your appointment for next month
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#cureclinic #restylane #flyingdoctor #jakartalifestyle #andrewuidjaja #aestheticdoctor #dokterestetikajakarta #travelingyogi #dokterestetikabali #aestheticdoctorbali #restylaneindonesia #asianguy #allerganmedicalinstitute #allergan #botox #filler #silhouettesoft #teosyal #skinbooster #threadlift #cellscience #tipscantik #dokterestetikamedan
Learning from one of the best trainers and plastic surgeons in the world. Thank you for sharing doctor @dalvihumzah @pdsurgery The Royal Society of Medicine, London - UK
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www.andrewuidjaja.com
#RoyalSocietyofMedicine #DalviHumzahAestheticTraining #LondonTrip #unitedkingdom #greatbritain #EuropeTrip
#RestylaneIndonesia #etihad
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#transformationday ‘Grow old like fine Wine, get better as we age’ A couple of weeks ago was my birthday. When you thought you were aging but then accidentally found your more than 13 years ago graduation picture, it confirmed that age (read: number) doesn’t define you #antiaging #fotokocak #gracefulaging #beforeandafter .
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#antiagingmedicine #yogilife #yogidoctor #flyingdoctor #andrewuidjaja #aestheticdoctor #dokterestetika
#practiceyogachangeyourworld
#asianmale #antiagingdoctor #aestheticdoctorbali #vieturabali #cellscience #dokterestetikajakarta #euroskinlab #birthdayboy
~How do you spell love? You don’t spell it. You feel it~•Pooh•
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#andrewuidjaja #adventurer #istanbullife #visitistanbul
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#Repost @cellscience.id
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Grand Opening Event
CellScience Solitaire Sofitel Bali
Rabu, 5 September 2018
Jewel Box Sofitel Bali Nusa Dua
Beach Resort, Bali
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Finally D-Day!!
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Pada hari spektakuler ini, CellScience mengadakan talkshow dengan tema 'Plastic Surgery vs Non Surgery' bersama Director Marble Plastic Surgery Hospital, Korea : Dr. Seo Ilbeom, dan CellScience Aesthetic Expert : Dr. Andrew Uidjaja
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Turut hadir juga Brand Ambassador CellScience @ranggamoela & @keziawarouw, serta Marble Brand Ambassador @leejeonghoon & @moa_aeim
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Mereka semua dengan seru membahas tentang plastic surgery dan perawatan non surgery yang bisa dilakukan, serta juga berbagi pengalaman masing2, semoga dapat menjawab pertanyaan semua teman - teman yang hadir
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@marbleps.indonesia
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"Your skin is who you are..."
#stayfabulouswithCELLSCIENCE
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Info Centre : +62 815 1111 2023
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