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In a new animation borne out of a fruitful collaboration between scientists at the @IMPVienna and the visualization team at #biolution, structural biologist Clemens Plaschka invites you on a journey into the nucleus of the eukaryotic cell to discover the secrets of regulated gene expression – drawing on some very recently published data. The video was produced using the visualization platform of biolution developed with advice by scientists of the IMP.
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Identification of gene
In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function.
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Dimethylmercury is an extremely potent neurotoxin and likely the most toxic compound of mercury. It is a volatile, flamnable, and colorless liquid with a sweet odor, although being close enough to smell this probably means you are doomed. Symptoms of poisoning are highly delayed and no effective treatments exist once symptoms appear. In 1996, Karen Wetterhahn, a chemistry professor at Dartmouth College who was an expert on toxic heavy metals, worked with dimethylmercury following all known safety precautions including a well-ventilated fume hood. When she spilled one or two drops on her gloved hand, she was unfazed and simply cleaned up then exchanged gloves. Nobody at the time knew that the compound easily permeated gloves and then the skin. Months later, Wetterhahn experienced abdominal pain and loss of coordination. Testing showed mercury levels 50x above normal. Despite all treatments, Wetterhahn lapsed into a non-responsive state and died ten months later at age 48. Unlike most organometallic compounds which tend to hydrolyze and violently catch fire, organomercury compounds are fairly stable, increasing their tendency to bioaccumulate. Uses of dimethylmercury included as a methylating reagent for synthesis, an NMR reference standard, and a toxicology reference. After the perilous dangers of dimethylmercury were revealed, it has been disrecommended to use for any purpose. #forbiddensnacks #chemistry #organicchemistry #inorganicchemistry #chemistrylab #chemistry_lab #chemistrylife #chemistrylifestyle #chemistryfun #chemistryisfun #chemistrylove #chemistrylovers #chemistrydaily #chemistrynotes #chemistryeducation #quimica #chemie #science #chemical #chemicals #molecule #molecules #moleculeoftheday #dimethylmercury #methylmercury #mercury #metal #heavymetal #toxic #toxin Requested by @notrealtrick
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